細川誠二郎研究室

細川研スケジュール

月ゼミ

2024/04/29

全合成
"Total Synthesis of Putative Melognine"
[main reactions] Michael addition, enyne methathesis, Jones oxidation
単離
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2024/04/22

全合成
"Total Synthesis of the Euphorbia Diterpenoid Pepluacetal"
[main reactions] Wolff rearrangement, Baeyer-Villiger oxidation, Mukaiyama aldol reaction, Wittig reaction, Dess-Martin oxidation, olefin metathesis, Eschenmoser methylenation
単離
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2024/04/15

全合成
"Ten-Gram-Scale Total Synthesis of the Anticancer Drug Candidate E7130 to Supply Clinical Trials"
[main reactions] Wittig reaction, Upjohn dihydroxylation, Malaprade oxidative cleavage, Appel reaction, Dess-Martin oxidation, NHK reaction, Michael addition, Claisen rearrangement, Swern oxidation, Shiina macrolactonization, HWE reaction
単離
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2024/04/08

全合成
"Total Synthesis of Dynobactin A"
[main reactions] Larock macrocyclization
単離
"Pullenvalenes A-D: Nitric Oxide-Mediated Transcriptional Activation (NOMETA) Enables Discovery of Triterpene Aminoglycosides from Australian Termite Nest-Derived Fungi"

2024/04/01

全合成
"Total Synthesis of Psammaplysins A, M, O, and Q and Ceratinamide A"
[main reactions] Baeyer-Villiger oxidation
単離
"Akedanones A-C, In Vitro and In Vivo Antiplasmodial 2,3-Dihydronaphthoquinones Produced by Streptomyces sp. K20-0187"